| Function | Keyboard Shortcut |
| Set LO frequency on tuned frequency (to be considered LO<->Tune Offset) | C |
| Enter new LO frequency | Ctrl+O or L |
| Enter new Tune frequency | Ctrl+T or T |
| Enter new Quick Tune frequency (auto LO) | Ctrl+Q or Q |
| Fast frequency input | 1 - 9 |
| Switch between LO A and B | Ctrl+V |
| Frequency Manager + Bands | Ctrl+B |
| Increase LO frequency by visible spectrum bandwidth | Ctrl+PageUp |
| Decrease LO frequency by visible spectrum bandwidth | Ctrl+PageDown |
| Select MouseWheelStep | Ctrl+Home or Menu |
| Increase Tune frequency by MouseWheelStep | Ctrl+Up |
| Decrease Tune frequency by MouseWheelStep | Ctrl+Down |
| Increase LO frequency by MouseWheelStep | Ctrl+Right |
| Decrease LO frequency by MouseWheelStep | Ctrl+Left |
| Enter new Locut frequency | Shift+L |
| Enter new Hicut frequency | Shift+H |
| Increase Locut frequency | Shift+Up |
| Decrease Locut frequency | Shift+Down |
| Increase Hicut frequency | Shift+Right |
| Decrease Hicut frequency | Shift+Left |
| Switch Mode to AM | Ctrl+A |
| Switch Mode to CW | Ctrl+C |
| Switch Mode to DRM | Ctrl+D |
| Switch Mode to ECSS | Ctrl+E |
| Switch Mode to FM | Ctrl+F |
| Switch Mode to LSB | Ctrl+L |
| Switch Mode to USB | Ctrl+U |
| NB – Noise Blanker RF | B |
| NB – Noise Blanker IF | I |
| NR – Noise Reduction | R |
| Manual Notch Filter (Beat Cancel) | N |
| Automatic Notch Filter (Auto Beat Cancel) | A |
| AGC (fast/mid/slow/off) | G |
| Mute on/off | M |
| Volume | +/- |
| Swap position of Waterfall/Spectrum | S |
| Swap position of RF/AF Display | Ctrl+S |
| Save current RF Waterfall to image file (in WAV recording directory) | Ctrl+W |
| Collapse Mode (only upper Display) | Shift+C |
| Compact Mode (without RF+AF Display) | Shift+X |
| Zoom RF Spectrum | Ctrl+'+' |
| UnZoom RF Spectrum | Ctrl+'-' |
| Reset RF Spectrum Zoom to full bandwidth | Ctrl+0 |
| Increase RF FFT Resolution Bandwidth (RBW) | Ctrl+'*' |
| Decrease RF FFT Resolution Bandwidth (RBW) | Ctrl+'/' |
| Zoom AF Spectrum | Shift+'+' |
| UnZoom AF Spectrum | Shift+'-' |
| Reset AF Spectrum Zoom to full bandwidth | Shift+0 |
| Increase AF FFT Resolution Bandwidth (RBW) | Shift+'*' |
| Decrease AF FFT Resolution Bandwidth (RBW) | Shift+'/' |
| S-meter calibration: Increase level | Shift+Up |
| S-meter calibration: Decrease level | Shift+Down |
| S-meter calibration: Reset level | Shift+Home |
| AFC | F |
| Set AFC carrier search range for AM/ECSS modes | Shift+A |
| CW ZAP | Z |
| CW Peak | P |
| CW Despreading | D |
| Switch between RX and TX | Space |
| TX mode: Switch CW carrier tone on/off | Return |
| Rewind WAV file | Shift+W or Shift+Home |
| Jump to next WAV file (Multipart WAV file only) | Shift+End |
| Switch WAV file looping | Shift+O |
| Record WAV file | Shift+R |
| Play WAV file | Shift+P |
| Stop Playback/Recording | Shift+S |
| Pause Playback/Recording | Shift+B or Space |
| Change WAV step size | Shift+K |
| Increase WAV file position by 'step size' | Shift+PageUp |
| Decrease WAV file position by 'step size' | Shift+PageDown |
| Show GUI of ExtIO-DLL | H |
| Help / Info / Update check | F1 |
| Start/Stop HDSDR | F2 |
| Minimize HDSDR | F3 |
| Exit HDSDR | F4 |
| Open sound card selection dialog | F5 |
| Open sampling rate dialog | F6 |
| Open Options menu | F7 |
| Full Screen | F11 |
| Boss Key | Pause |